Product Number |
OAAN02418 |
Product Page |
www.avivasysbio.com/bag2-antibody-oaan02418.html |
Name |
BAG2 Antibody (OAAN02418) |
Molecular Weight |
24 kDa |
Isotype |
IgG |
Conjugation |
Unconjugated |
NCBI Gene Id |
9532 |
Host |
Rabbit |
Clonality |
Polyclonal |
Gene Full Name |
BCL2 associated athanogene 2 |
Alias Symbols |
BAG-2, dJ417I1.2 |
Product Format |
Liquid |
Description of Target |
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-BAG2 (OAAN02418) |
Application Info |
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200 |
Immunogen |
Recombinant protein of human BAG2 |
Storage Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Uniprot ID |
O95816 |
Protein Name |
BAG family molecular chaperone regulator 2 |
Protein Accession # |
NP_004273.1 |
Purification |
Affinity purified against immunogen |
Nucleotide Accession # |
NM_004282.3 |
Preservative |
0.02% Sodium Azide |
Gene Symbol |
BAG2 |
Predicted Species Reactivity |
Human, Mouse, Rat |
Application |
WB, IHC |
Image 1 | Multiple Cell Types
| Western blot analysis of extracts of various cells, using BAG2 antibody. |
| Image 2 | Human Kidney,Multiple Cell Types
| Immunohistochemistry of paraffin-embedded human kidney using BAG2 antibody at dilution of 1:100 (40x lens). |
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