RAMP3 Antibody (OAAN01968)

• Product Number: OAAN01968
• Name: RAMP3 Antibody (OAAN01968)
• Molecular Weight: 16 kDa
• Isotype: IgG
• Conjugation: Unconjugated
• NCBI Gene Id: 10268
• Host: Rabbit
• Clonality: Polyclonal
• Gene Full Name: receptor (G protein-coupled) activity modifying protein 3
• Alias Symbols: , receptor (G protein-coupled) activity modifying protein 3, Receptor activity-modifying protein 3, RAMP3
• Product Format: Liquid
• Description of Target: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Application Info: WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:10 - 1:100
• Immunogen: Recombinant protein of human RAMP3
• Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Uniprot ID: O60896
• Protein Name: Receptor activity-modifying protein 3
• Protein Accession #: NP_005847.1
• Purification: Affinity purified against immunogen
• Nucleotide Accession #: NM_005856.2
• Preservative: 0.02% Sodium Azide
• Gene Symbol: RAMP3
• Predicted Species Reactivity: Human, Mouse, Rat
• Application: WB, IHC, IF
• Image 1: Multiple Cell Lines
  
  Western blot analysis of extracts of various cell lines, using RAMP3 antibody.
• Image 2: MCF-7,Multiple Cell Lines
  
  Immunofluorescence analysis of MCF-7 cell using RAMP3 antibody. Blue: DAPI for nuclear staining.