| Product Number |
OAAN00972 |
| Product Page |
www.avivasysbio.com/cpt2-antibody-oaan00972.html |
| Name |
CPT2 Antibody (OAAN00972) |
| Molecular Weight |
74 kDa |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
1376 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
carnitine palmitoyltransferase 2 |
| Description |
|
| Alias Symbols |
CPT1, IIAE4, CPTASE |
| Product Format |
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH 7.3 |
| Description of Target |
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. |
| Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CPT2 (OAAN00972) |
| Application Info |
WB: 1:500~2000
IHC: 1:50~100
IF: 1:50~100
|
| Immunogen |
A synthetic peptide of human CPT2. |
| Intended Use |
For research purposes only. Not for therapeutic or diagnostic purposes in humans or animals. |
| Uniprot ID |
P23786 |
| Protein Name |
Carnitine O-palmitoyltransferase 2, mitochondrial |
| Publications |
A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. Sci Adv. 7, eabi7514 (2021). 34559558
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation. Aging (Albany NY). 12, 19677-19700 (2020). 33024056 |
| Protein Accession # |
NP_000089.1 |
| Purification |
Affinity purified against immunogen. |
| Nucleotide Accession # |
NM_000098.2 |
| Gene Symbol |
CPT2 |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB, IHC, IF |
| Image 1 | Multiple Cell Lines
 | Western blot analysis of extracts of various cell lines, using CPT2 antibody. |
|
| Image 2 | Human Esophagus
 | Immunohistochemistry of paraffin-embedded human esophagus cancer tissue using CPT2 antibody. |
|
| Image 3 | Rat Kidney
 | Immunohistochemistry of paraffin-embedded Rat kidney using CPT2 antibody at dilution of 1:100 (x40 lens). |
|
| Image 4 | Liver Cancer
 | Immunohistochemistry of paraffin-embedded liver cancer using CPT2 antibody at dilution of 1:100 (x40 lens). |
|
| Image 5 | Mouse Kidney
 | Immunohistochemistry of paraffin-embedded mouse kidney using CPT2 antibody at dilution of 1:100 (x40 lens). |
|
| Image 6 | MCF7 Cells,Human Esophagus,Rat Kidney,Liver Cancer,Mouse Kidney,Multiple Cell Lines
 | Immunofluorescence analysis of MCF7 cell using CPT2 antibody. Blue: DAPI for nuclear staining. |
|
