| Product Number |
OAAN00749 |
| Product Page |
www.avivasysbio.com/nr1h3-antibody-oaan00749.html |
| Name |
NR1H3 Antibody (OAAN00749) |
| Molecular Weight |
50 kDa |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
10062 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
nuclear receptor subfamily 1 group H member 3 |
| Alias Symbols |
LXRA, LXR-a, RLD-1 |
| Product Format |
Liquid |
| Description of Target |
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR1H3 (OAAN00749) |
| Application Info |
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200 |
| Immunogen |
Recombinant protein of human NR1H3 |
| Storage Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot ID |
Q13133 |
| Protein Name |
Oxysterols receptor LXR-alpha |
| Protein Accession # |
NP_001123573.1 |
| Purification |
Affinity purified against immunogen |
| Nucleotide Accession # |
NM_001130101.2 |
| Preservative |
0.02% Sodium Azide |
| Gene Symbol |
NR1H3 |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB, IHC |
| Image 1 | Multiple Cell Types
 | Western blot analysis of extract of various cells, using NR1H3 antibody. |
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