| Product Number |
OAAN00709 |
| Product Page |
www.avivasysbio.com/fgr-antibody-oaan00709.html |
| Name |
FGR Antibody (OAAN00709) |
| Molecular Weight |
56 kDa |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
2268 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
FGR proto-oncogene, Src family tyrosine kinase |
| Alias Symbols |
SRC2, c-fgr, c-src2, p55-Fgr, p58-Fgr, p55c-fgr, p58c-fgr |
| Product Format |
Liquid |
| Description of Target |
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Reconstitution and Storage |
Store at -20C. Avoid repeated freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FGR (OAAN00709) |
| Application Info |
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200 |
| Immunogen |
A synthetic peptide of human FGR |
| Storage Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot ID |
P09769 |
| Protein Name |
Tyrosine-protein kinase Fgr |
| Protein Accession # |
NP_001036194.1 |
| Purification |
Affinity purified against immunogen |
| Nucleotide Accession # |
NM_001042729.1 |
| Preservative |
0.02% Sodium Azide |
| Gene Symbol |
FGR |
| Predicted Species Reactivity |
Human, Rat |
| Application |
WB, IHC |
| Image 1 | HL60
 | Western blot analysis of extracts of HL60 cell lines, using FGR antibody. |
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