| Product Number |
OAAJ07639 |
| Product Page |
www.avivasysbio.com/pawr-antibody-oaaj07639.html |
| Name |
PAWR Antibody (OAAJ07639) |
| Molecular Weight |
37 kDa |
| NCBI Gene Id |
5074 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/mL |
| Alias Symbols |
PAR4, Par-4 |
| Product Format |
Liquid |
| Description of Target |
Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1. |
| Reconstitution and Storage |
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PAWR (OAAJ07639) antibody |
| Immunogen |
A synthetic peptide of human PRKC |
| Uniprot ID |
Q96IZ0 |
| Protein Name |
PRKC apoptosis WT1 regulator protein |
| Protein Accession # |
NP_002574 |
| Purification |
Immunogen affinity chromatography |
| Nucleotide Accession # |
NM_002583 |
| Gene Symbol |
PAWR |
| Predicted Species Reactivity |
Human, Mouse, Rat |
| Application |
WB, IHC |
| Image 1 | various cell lines
 | Western blot analysis of extracts of various celllines, using PAWR antibody. |
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