PICK1 Antibody (OAAJ06912)

Data Sheet
 
Product Number OAAJ06912
Product Page www.avivasysbio.com/pick1-antibody-oaaj06912.html
Name PICK1 Antibody (OAAJ06912)
Molecular Weight 47 kDa
NCBI Gene Id 9463
Host Rabbit
Clonality Polyclonal
Concentration 1 mg/mL
Alias Symbols PICK, PRKCABP
Product Format Liquid
Description of Target Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
Reconstitution and Storage Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for anti-PICK1 (OAAJ06912) antibody
Immunogen A synthetic peptideof human PICK1
Uniprot ID Q9NRD5
Protein Name PRKCA-binding protein
Protein Accession # NP_001034672
Purification Immunogen affinity chromatography
Nucleotide Accession # NM_001039583
Gene Symbol PICK1
Predicted Species Reactivity Human, Mouse, Rat
Application WB, IHC
Image 1
various cell lines
Western blot analysis of extracts of variouscell lines, using PICK1 antibody.
 

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