Anti-OCT-2 Antibody (OAAI00239)

Data Sheet
 
Product Number OAAI00239
Product Page www.avivasysbio.com/anti-oct-2-antibody-oaai00239.html
Name Anti-OCT-2 Antibody (OAAI00239)
Molecular Weight 55-60
Isotype Rabbit IgG
NCBI Gene Id 5452
Host Rabbit
Clonality Polyclonal
Concentration 100ug/200ul
Gene Full Name POU class 2 homeobox 2
Alias Symbols homeobox protein;lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;Oct-2;OCT2;octamer-binding protein 2;octamer-binding transcription factor 2;OTF2;POU domain, class 2, transcription factor 2.
Product Format Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Reference Daniel Re, et al. Oct-2 and Bob-1 Deficiency in Hodgkin and Reed Sternberg Cells. Cancer Research 61, 2080-2084 (2001).
Description of Target Oct1 and Oct2 are transcription factors of the POU homeo-domain family that bind to the lg gene octamer sites, regulating B-cell-specific genes. The function of these transcription factors is dependent on the activity of B-cell-restricted coactivators such as BOB.1/OBF.1.Absence of functional Oct-2 and Bob-1 cells represents a novel mechanism for immunoglobulin gene deregulation
Reconstitution and Storage The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Datasheets/Manuals Printable datasheet for Anti-OCT-2 Antibody (OAAI00239)
Specificity POU2F2
Additional Information Background: Oct1 and Oct2 are transcription factors of the POU homeo-domain family that bind to the Ig gene octamer sites, regulating B-cell-specific genes. The function of these transcription factors is dependent on the activity of B-cell-restricted coactivators such as BOB.1/OBF.1.Absence of functional Oct-2 and Bob-1 cells represents a novel mechanism for immunoglobulin gene deregulation
Additional Information Positive Control: Jurkat Cell Lysate
Application Info WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
Immunogen A synthetic peptide corresponding to C-terminus of OCT-2 protein from human, mouse and rat origins.
Additional Information Cellular Location: Nuclear
Formulation This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Uniprot ID P06400
Purification Affinity Purified
Gene Symbol POU2F2
Predicted Species Reactivity Human|Mouse|Rat
Application Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
Image 1
Phospho-peptide, non-phospho-peptide
Dot Blot: 1 ?g peptides was blotted onto NC membrane A: OCT-1 B: OCT-2 C: OCT-4 Followed by immunoblotting at a 1:1000 dilution by: 1: Rabbit anti-OCT-1(Cat#OAAI00487) 2: Rabbit anti-OCT-2(Cat#OAAI00239) 3: Rabbit anti-OCT-4 (OAAI00488)
 

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