Product Number |
OAAF08106 |
Product Page |
www.avivasysbio.com/sema4d-antibody-oaaf08106.html |
Name |
SEMA4D Antibody (OAAF08106) |
Molecular Weight |
96 kDa |
Isotype |
IgG |
NCBI Gene Id |
10507 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1mg/ml |
Gene Full Name |
semaphorin 4D |
Alias Symbols |
A8;BB18;C9orf164;CD100;coll-4;COLL4;GR3;M-sema-G;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D;SEMAJ;semaphorin-4D. |
Peptide Sequence |
Synthetic peptide located within the following region: TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLN |
Product Format |
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Description of Target |
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. |
Reconstitution and Storage |
-20°C |
Datasheets/Manuals |
Printable datasheet for SEMA4D Antibody (OAAF08106) |
Specificity |
SEMA4D Antibody detects endogenous levels of SEMA4D protein. |
Application Info |
WB 1:500~1000
ELISA 1:10000
|
Immunogen |
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SEMA4D. |
Uniprot ID |
Q92854 |
Protein Name |
Semaphorin-4D |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide. |
Gene Symbol |
SEMA4D |
Predicted Species Reactivity |
Human|Mouse|Rat |
Application |
Enzyme-linked immunosorbent assay|Western blot |
Image 1 | MCF7 cells
| Western blot analysis of lysate from MCF7 cells, using SEMA4D Antibody. |
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