SEMA4D Antibody (OAAF08106)

Data Sheet
 
Product Number OAAF08106
Product Page www.avivasysbio.com/sema4d-antibody-oaaf08106.html
Name SEMA4D Antibody (OAAF08106)
Molecular Weight 96 kDa
Isotype IgG
NCBI Gene Id 10507
Host Rabbit
Clonality Polyclonal
Concentration 1mg/ml
Gene Full Name semaphorin 4D
Alias Symbols A8;BB18;C9orf164;CD100;coll-4;COLL4;GR3;M-sema-G;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D;SEMAJ;semaphorin-4D.
Peptide Sequence Synthetic peptide located within the following region: TLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLN
Product Format Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Description of Target Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Reconstitution and Storage -20°C
Datasheets/Manuals Printable datasheet for SEMA4D Antibody (OAAF08106)
Specificity SEMA4D Antibody detects endogenous levels of SEMA4D protein.
Application Info WB 1:500~1000
ELISA 1:10000
Immunogen The antiserum was produced against synthesized peptide derived from the N-terminal region of human SEMA4D.
Uniprot ID Q92854
Protein Name Semaphorin-4D
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Gene Symbol SEMA4D
Predicted Species Reactivity Human|Mouse|Rat
Application Enzyme-linked immunosorbent assay|Western blot
Image 1
MCF7 cells
Western blot analysis of lysate from MCF7 cells, using SEMA4D Antibody.
 

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