Product Number |
OAAF05547 |
Product Page |
www.avivasysbio.com/map2k7-antibody-phospho-ser271-oaaf05547.html |
Name |
MAP2K7 Antibody (Phospho-Ser271) (OAAF05547) |
Molecular Weight |
47 kDa |
Isotype |
IgG |
NCBI Gene Id |
5609 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Description |
|
Alias Symbols |
MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4 |
Product Format |
LiquidPBS (without Mg2+ and Ca2+) (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol |
Reconstitution and Storage |
Store at -20°C/1 year |
Datasheets/Manuals |
Printable datasheet for OAAF05547 |
Specificity |
MAP2K7 (Phospho-Ser271) Antibody detects endogenous levels of MAP2K7 only when phosphorylated at S271 |
Additional Information |
Modification Sites: Human: S271, Mouse: S287, Rat: S271 |
Immunogen |
The antiserum was produced against synthesized phospho-peptide derived from the Internal region of human MAP2K7 around the phosphorylation site of S271. |
Uniprot ID |
O14733 |
Publications |
Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 7, 10592 (2016). 26882989
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. Nat. Med. 23, 439-449 (2017). 28218919 |
Purification |
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
Target Post-Translational Modification |
Phospho |
Gene Symbol |
MAP2K7 |
Predicted Species Reactivity |
Human, Mouse, Rat |
Application |
WB, IHC, ELISA |
Image 1 | NIH-3T3 cells
| Western blot analysis of extracts from NIH-3T3 cells treated with insulin 0.01U/ml 15' and NIH-3T3 cells treated with EGF 200ng/ml 30', using MAP2K7 (Phospho-Ser271) Antibody. |
| Image 2 | MAP2K7 (Phospho-Ser271)
| Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using MAP2K7 (Phospho-Ser271) Antibody |
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