| Product Number |
OAAF02732 |
| Product Page |
www.avivasysbio.com/med13-antibody-oaaf02732.html |
| Name |
MED13 Antibody (OAAF02732) |
| Molecular Weight |
239 kDa |
| NCBI Gene Id |
9969 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
mediator complex subunit 13 |
| Alias Symbols |
activator-recruited cofactor 250 kDa component;ARC250;DRIP250;HSPC221;Mediator complex subunit 13;mediator of RNA polymerase II transcription subunit 13;mediator of RNA polymerase II transcription, subunit 13 homolog;MRD61;THRAP1;thyroid hormone receptor-associated protein 1;thyroid hormone receptor-associated protein complex 240 kDa component;thyroid hormone receptor-associated protein complex component TRAP240;thyroid hormone receptor-associated protein, 240 kDa subunit;TRAP240;vitamin D3 receptor-interacting protein complex component DRIP250. |
| Product Format |
Liquid |
| Reference |
Olsen J.V., Cell 127:635-648(2006).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Naeaer A.M., Nature 398:828-832(1999). |
| Description of Target |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for MED13 Antibody (OAAF02732) |
| Specificity |
MED13 antibody detects endogenous levels of total MED13 protein. |
| Application Info |
IHC: 1:50~1:100; ELISA: 1:40000 |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human MED13. |
| Dilution |
The optimal working dilution should be determined by the end user. |
| Formulation |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot ID |
Q9UHV7 |
| Protein Name |
Mediator of RNA polymerase II transcription subunit 13 |
| Protein Accession # |
NP_005112.2 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Gene Symbol |
MED13 |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin |
| Image 1 | human lung carcinoma
 | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using MED13 Antibody. The picture on the right is treated with the synthesized peptide. |
|
|
