| Product Number |
OAAF02253 |
| Product Page |
www.avivasysbio.com/acvrl1-antibody-oaaf02253.html |
| Name |
ACVRL1 Antibody (OAAF02253) |
| Molecular Weight |
56 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
94 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
activin A receptor like type 1 |
| Alias Symbols |
activin A receptor type II-like 1;activin A receptor type IL;activin A receptor, type II-like kinase 1;Activin receptor-like kinase 1;ACVRLK1;ALK1;ALK-1;HHT;HHT2;ORW2;serine/threonine-protein kinase receptor R3;SKR3;TGF-B superfamily receptor type I;TSR-I. |
| Product Format |
Liquid in PBS (without Mg2+ and Ca2+) pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol |
| Reference |
ten Dijke P., Oncogene 8:2879-2887(1993).
Attisano L., Cell 75:671-680(1993).
Berg J.N., Am. J. Hum. Genet. 61:60-67(1997). |
| Description of Target |
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for ACVRL1 Antibody (OAAF02253) |
| Specificity |
ACVL1 antibody detects endogenous levels of total ACVL1 protein. |
| Application Info |
WB: 1:500~1000
IHC: 1:50~100
IF: 1:100~500
ELISA: 1:20000 |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human ACVL1. |
| Dilution |
The optimal working dilution should be determined by the end user. |
| Uniprot ID |
P37023 |
| Protein Name |
Serine/threonine-protein kinase receptor R3 |
| Protein Accession # |
NP_000011.2 |
| Purification |
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Gene Symbol |
ACVRL1 |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | human breast carcinoma tissue
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ACVL1 Antibody. The picture on the right is treated with the synthesized peptide. |
|
| Image 2 | HeLa cells
 | Immunofluorescence analysis of HeLa cells, using ACVL1 Antibody. The picture on the right is treated with the synthesized peptide. |
|
| Image 3 | K562 cells
 | Western blot analysis of extracts from K562 cells, using ACVL1 Antibody. The lane on the right is treated with the synthesized peptide. |
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