| Product Number |
OAAF02119 |
| Product Page |
www.avivasysbio.com/ngfr-antibody-oaaf02119.html |
| Name |
NGFR Antibody (OAAF02119) |
| Molecular Weight |
45 kDa |
| NCBI Gene Id |
4804 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
nerve growth factor receptor |
| Alias Symbols |
CD271;Gp80-LNGFR;low affinity neurotrophin receptor p75NTR;low-affinity nerve growth factor receptor;NGF receptor;p75 ICD;p75(NTR);p75NTR;TNFR superfamily, member 16;TNFRSF16;tumor necrosis factor receptor superfamily member 16. |
| Product Format |
Liquid |
| Reference |
Ye X., J. Biol. Chem. 274:30202-30208(1999).
Wooten M.W., J. Biol. Chem. 276:7709-7712(2001).
Bai D., Biochem. Biophys. Res. Commun. 309:552-557(2003). |
| Description of Target |
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver. |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for NGFR Antibody (OAAF02119) |
| Specificity |
TNR16 antibody detects endogenous levels of total TNR16 protein. |
| Application Info |
WB: 1:500~1:3000; IF: 1:100~1:500; ELISA: 1:40000 |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human TNR16. |
| Dilution |
The optimal working dilution should be determined by the end user. |
| Formulation |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot ID |
P08138 |
| Protein Name |
Tumor necrosis factor receptor superfamily member 16 |
| Protein Accession # |
NP_002498.1 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Gene Symbol |
NGFR |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot |
| Image 1 | A549 cells
 | Immunofluorescence analysis of A549 cells, using TNR16 Antibody. The picture on the right is treated with the synthesized peptide. |
|
| Image 2 | HepG2 cells
 | Western blot analysis of extracts from HepG2 cells, using TNR16 Antibody. The lane on the right is treated with the synthesized peptide. |
|
