| Product Number |
OAAF01948 |
| Product Page |
www.avivasysbio.com/cd40-antibody-oaaf01948.html |
| Name |
CD40 Antibody (OAAF01948) |
| Molecular Weight |
30 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
958 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
CD40 molecule |
| Alias Symbols |
B cell surface antigen CD40;B cell-associated molecule;B-cell surface antigen CD40;Bp50;CD40 molecule, TNF receptor superfamily member 5;CD40L receptor;CDW40;p50;TNFRSF5;tumor necrosis factor receptor superfamily member 5. |
| Product Format |
Liquid; phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Reference |
Carlos Reyes-Moreno, J. Biol. Chem., May 2007; 10.1074.
Hongwei Qin, Blood, Nov 2005; 106: 3114 - 3122.
Meera J. Nathan, J. Immunol., Jun 2004; 172: 6626 - 6633.
Clare C. Davies, Mol. Cell. Biol., Nov 2005; 25: 9806 - 9819. |
| Description of Target |
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for CD40 Antibody (OAAF01948) |
| Specificity |
CD40 antibody detects endogenous levels of total CD40 protein. |
| Application Info |
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000 |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human CD40. |
| Dilution |
The optimal working dilution should be determined by the end user. |
| Uniprot ID |
P25942 |
| Protein Name |
Tumor necrosis factor receptor superfamily member 5 |
| Protein Accession # |
NP_001241.1 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Gene Symbol |
CD40 |
| Predicted Species Reactivity |
Human|Monkey|Mouse |
| Application |
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | human breast carcinoma tissue
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CD40 Antibody. The picture on the right is treated with the synthesized peptide. |
| | Image 2 | COS7 cells
 | Western blot analysis of extracts from COS7 cells, using CD40 Antibody. The lane on the right is treated with the synthesized peptide. |
|
|
