| Product Number |
OAAF00641 |
| Product Page |
www.avivasysbio.com/myc-antibody-oaaf00641.html |
| Name |
Myc Antibody (OAAF00641) |
| Molecular Weight |
48 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
4609 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1 mg/ml |
| Gene Full Name |
MYC proto-oncogene, bHLH transcription factor |
| Alias Symbols |
avian myelocytomatosis viral oncogene homolog;bHLHe39;class E basic helix-loop-helix protein 39;c-Myc;MRTL;myc proto-oncogene protein;MYCC;myc-related translation/localization regulatory factor;proto-oncogene c-Myc;transcription factor p64;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog. |
| Product Format |
Liquid (without Mg2+ and Ca2+) (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol |
| Reference |
Markus Welcker, PNAS, Jun 2004; 101: 9085 - 9090.
Mark A. Gregory, J. Biol. Chem., Dec 2003; 278: 51606 - 51612.
David W. Chang, Mol. Cell. Biol., Jun 2000; 20: 4309 - 4319.
Rosalie Sears, Genes & Dev., Oct 2000; 14: 2501. |
| Description of Target |
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000). |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for Myc Antibody (OAAF00641) |
| Specificity |
Myc antibody detects endogenous levels of total Myc protein. |
| Application Info |
WB: 1:500~1000
IHC: 1:50~100
IF: 1:100~500
ELISA: 1:40000 |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human MYC. |
| Uniprot ID |
P01106 |
| Protein Name |
Myc proto-oncogene protein |
| Protein Accession # |
NP_002458.2 |
| Purification |
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Gene Symbol |
MYC |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | human breast carcinoma tissue
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MYC Antibody. The picture on the right is treated with the synthesized peptide. |
|
| Image 2 | HeLa cells
 | Immunofluorescence analysis of HeLa cells, using MYC Antibody. The picture on the right is treated with the synthesized peptide. |
|
| Image 3 | HeLa cells
 | Western blot analysis of extracts from HeLa cells, treated with Forskolin 40nM 30', using MYC Antibody. The lane on the right is treated with the synthesized peptide. |
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