MAPK6 Antibody (Phospho-Ser189) (OAAB18261)

Data Sheet
 
Product Number OAAB18261
Product Page www.avivasysbio.com/mapk6-antibody-phospho-s189-oaab18261.html
Name MAPK6 Antibody (Phospho-Ser189) (OAAB18261)
Molecular Weight 83 kDa, 82 kDa
Isotype Rabbit Ig
NCBI Gene Id 5597
Host Rabbit
Clonality Polyclonal
Alias Symbols ERK3, PRKM6, p97MAPK, HsT17250
Product Format Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reference Rai, R., et al., Oral Oncol. 40(7):705-712 (2004).
Coulombe, P., et al., Mol. Cell. Biol. 24(14):6140-6150 (2004).
Coulombe, P., et al., Mol. Cell. Biol. 23(13):4542-4558 (2003).
Julien, C., et al., J. Biol. Chem. 278(43):42615-42624 (2003).
Robinson, M.J., et al., J. Biol. Chem. 277(7):5094-5100 (2002).
Description of Target ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB18261
Application Info IHC-P: 1:50~100
Immunogen This Phospho-ERK3-S189 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S189 of human ERK3.
Uniprot ID Q16659, P27704, Q61532, Q5F3W3
Protein Accession # NP_002739.1
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Gene Symbol MAPK6
Predicted Species Reactivity Mouse, Rat
Application IHC
Predicted Homology Based on Immunogen Sequence Mouse; Rat
Image 1
Human cancer tissue
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
BC = breast carcinoma; HC = hepatocarcinoma.
Dilution: 1:50~100
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com