PPP3CA Antibody - N-terminal region (OAAB17635)

Data Sheet
 
Product Number OAAB17635
Product Page www.avivasysbio.com/calcineurin-ppp3ca-antibody-n-terminal-region-oaab17635.html
Name PPP3CA Antibody - N-terminal region (OAAB17635)
Molecular Weight 58688 Da
Isotype Ig
NCBI Gene Id 5530
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols CALN, CCN1, CNA1, CALNA, DEE91, IECEE, PPP2B, ACCIID, CALNA1, IECEE1
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Description of Target Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB17635
Additional Information Precautions: Calcineurin (PPP3CA) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1
Application Info WB: 1:1000
IHC-P: 1:50~100
Immunogen This Calcineurin (PPP3CA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human Calcineurin (PPP3CA).
Additional Information Cellular Location: Nucleus (By similarity). Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle (By similarity)
Uniprot ID Q08209
Protein Name Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Protein Accession # NP_000935.1
Gene Symbol PPP3CA
Predicted Species Reactivity Human, Mouse
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Human; Mouse
Image 1
breast carcinoma
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Image 2
Mouse Kidney
Western blot analysis of anti-PPP3CA Pab (Cat. # OAAB17635) in mouse kidney tissue lysate.PPP3CA(arrow) was detected using the purified Pab.
 

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