Product Number |
OAAB17635 |
Product Page |
www.avivasysbio.com/calcineurin-ppp3ca-antibody-n-terminal-region-oaab17635.html |
Name |
PPP3CA Antibody - N-terminal region (OAAB17635) |
Molecular Weight |
58688 Da |
Isotype |
Ig |
NCBI Gene Id |
5530 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
CALN, CCN1, CNA1, CALNA, DEE91, IECEE, PPP2B, ACCIID, CALNA1, IECEE1 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB17635 |
Additional Information |
Precautions: Calcineurin (PPP3CA) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1 |
Application Info |
WB: 1:1000 IHC-P: 1:50~100 |
Immunogen |
This Calcineurin (PPP3CA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human Calcineurin (PPP3CA). |
Additional Information |
Cellular Location: Nucleus (By similarity). Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle (By similarity) |
Uniprot ID |
Q08209 |
Protein Name |
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
Protein Accession # |
NP_000935.1 |
Gene Symbol |
PPP3CA |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | breast carcinoma
| Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
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Image 2 | Mouse Kidney
| Western blot analysis of anti-PPP3CA Pab (Cat. # OAAB17635) in mouse kidney tissue lysate.PPP3CA(arrow) was detected using the purified Pab. |
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