DUSP10 Antibody - N-terminal region (OAAB17619)

• Product Number: OAAB17619
• Name: DUSP10 Antibody - N-terminal region (OAAB17619)
• Molecular Weight: 52642 Da
• Isotype: Ig
• NCBI Gene Id: 11221
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: MKP5, MKP-5
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: DUSP10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This DUSP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP10.
• Additional Information: Cellular Location: Cytoplasm. Nucleus.
  Tissue Location: Detected in brain.
• Uniprot ID: Q9Y6W6
• Protein Name: Dual specificity protein phosphatase 10
• Protein Accession #: NP_009138.1
• Gene Symbol: DUSP10
• Predicted Species Reactivity: Human, Mouse
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Image 1: Human Testis
  
  Formalin-fixed and paraffin-embedded human testis tissue reacted with DUSP10 Antibody (N-term) (Cat.# OAAB17619), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
• Image 2: breast carcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
• Image 3: CEM
  
  Western blot analysis of anti-DUSP10 Pab (Cat. # OAAB17619) in CEM cell line tissue lysate (35ug/lane). DUSP10(arrow) was detected using the purified Pab (1:60 dilution).
• Image 4: Mouse Heart
  
  Western blot analysis of anti-DUSP10 Pab (Cat. # OAAB17619) in mouse heart tissue lysates (35ug/lane). DUSP10(arrow) was detected using the purified Pab (1:60 dilution).