| Product Number |
OAAB17591 |
| Product Page |
www.avivasysbio.com/step-ptpn5-antibody-n-terminal-region-oaab17591.html |
| Name |
STEP / PTPN5 Antibody - N-terminal region (OAAB17591) |
| Molecular Weight |
63538 Da |
| Isotype |
Ig |
| NCBI Gene Id |
84867 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
STEP, STEP61, PTPSTEP |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17591 |
| Additional Information |
Precautions: STEP / PTPN5 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors |
| Application Info |
WB: 1:1000
IHC-P: 1:10~50 |
| Immunogen |
This STEP / PTPN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the N-terminal region of human STEP / PTPN5. |
| Additional Information |
Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity) |
| Uniprot ID |
P54829 |
| Protein Name |
Tyrosine-protein phosphatase non-receptor type 5 |
| Protein Accession # |
NP_001035059.1 |
| Gene Symbol |
PTPN5 |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
| Image 1 | Mouse Brain
 | Western blot analysis of hSTEP-Q155 (Cat. # OAAB17591) in mouse brain tissue lysates (35ug/lane). STEP (arrow) was detected using the purified Pab |
| | Image 2 | HepG2
 | Western blot analysis of hSTEP-Q155 (Cat. # OAAB17591) in HepG2 cell line lysates (35ug/lane). STEP (arrow) was detected using the purified Pab. |
| | Image 3 | Human Brain
 | Formalin-fixed and paraffin-embedded human brain tissue reacted with STEP antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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