GUCY1A2 Antibody - C-terminal region (OAAB17565)

• Product Number: OAAB17565
• Name: GUCY1A2 Antibody - C-terminal region (OAAB17565)
• Molecular Weight: 81750 Da
• Isotype: Ig
• NCBI Gene Id: 2977
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: GC-SA2, GUC1A2
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: Guanylyl Cyclase alpha 2 (GUCY1A2) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Has guanylyl cyclase on binding to the beta-1 subunit.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This Guanylyl Cyclase alpha 2 (GUCY1A2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 699-732 amino acids from the C-terminal region of human Guanylyl Cyclase alpha 2 (GUCY1A2).
• Additional Information: Cellular Location: Cytoplasm.
  Tissue Location: Isoform 1 is expressed in fetal brain, liver, colon, endothelium and testis. Isoform 2 is expressed only in liver, colon and endothelium
• Uniprot ID: P33402
• Protein Name: Guanylate cyclase soluble subunit alpha-2
• Sample Type Confirmation:

  GUCY1A2 is strongly supported by BioGPS gene expression data to be expressed in NCI-H460

• Protein Accession #: NP_000846.1
• Gene Symbol: GUCY1A2
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: NCI-H460
  
  Western blot analysis of anti-GUCY1A2 Antibody (C-term) (Cat.# OAAB17565) in NCI-H460 cell line lysates (35ug/lane). GUCY1A2 (arrow) was detected using the purified Pab.

  GUCY1A2 is strongly supported by BioGPS gene expression data to be expressed in NCI-H460

• Image 2: breast carcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.