| Product Number |
OAAB17466 |
| Product Page |
www.avivasysbio.com/tlk1-antibody-c-terminal-region-oaab17466.html |
| Name |
TLK1 Antibody - C-terminal region (OAAB17466) |
| Molecular Weight |
87 kDa |
| Isotype |
Ig |
| NCBI Gene Id |
9874 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Varies by lot. See vial for concentration. |
| Alias Symbols |
PKU-beta |
| Product Format |
Liquid PBS with 0.09% (W/V) sodium azide. |
| Description of Target |
The Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly |
| Reconstitution and Storage |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17466 |
| Application Info |
WB: 1:8000
IHC-P: 1:50~100 |
| Immunogen |
This TLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-750 amino acids from the C-terminal region of human TLK1. |
| Additional Information |
Cellular Location: Nucleus.
Tissue Location: Widely expressed. Present in fetal placenta, liver, kidney and pancreas but not heart or skeletal muscle. Also found in adult cell lines. Isoform 3 is ubiquitously expressed in all tissues examined |
| Uniprot ID |
Q9UKI8 |
| Protein Name |
Serine/threonine-protein kinase tousled-like 1 |
| Sample Type Confirmation |
TLK1 is strongly supported by BioGPS gene expression data to be expressed in K562 |
| Protein Accession # |
NP_001130026.1 |
| Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Gene Symbol |
TLK1 |
| Predicted Species Reactivity |
Human |
| Application |
WB, IHC |
| Image 1 | hepatocarcinoma
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
| | Image 2 | K562
 | Western blot analysis of hTLK1-L687 (Cat. # OAAB17466) in K562 cell line lysates (35ug/lane). TLK1 (arrow) was detected using the purified Pab. TLK1 is strongly supported by BioGPS gene expression data to be expressed in K562 |
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