PACSIN3 Antibody - N-terminal region (OAAB17453)

• Product Number: OAAB17453
• Name: PACSIN3 Antibody - N-terminal region (OAAB17453)
• Molecular Weight: 48487 Da
• Isotype: Ig
• NCBI Gene Id: 29763
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: SDPIII
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: PACSIN3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: May play a role in endocytosis (By similarity).
• Application Info: WB: 1:2000
  IHC-P: 1:50~100
• Immunogen: This PACSIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PACSIN3.
• Additional Information: Cellular Location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Note=Detected at the inner aspect of the plasma membrane in myotubes (By similarity)
  Tissue Location: Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney
• Uniprot ID: Q9UKS6
• Protein Name: Protein kinase C and casein kinase substrate in neurons protein 3
• Protein Accession #: NP_001171903.1
• Gene Symbol: PACSIN3
• Predicted Species Reactivity: Human, Mouse
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Image 1: Mouse Brain
  
  The anti-PACSIN3 Pab (Cat. # OAAB17453) is used in Western blot to detect PACSIN3 in mouse brain tissue lysate.
• Image 2: 293
  
  PACSIN3 Antibody (M1) (Cat. # OAAB17453) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PACSIN3 antibody detected the PACSIN3 protein (arrow).
• Image 3: 293
  
  Western blot analysis of PACSIN3 (arrow) using rabbit polyclonal PACSIN3 Antibody (M1) (Cat. # OAAB17453). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PACSIN3 gene.
• Image 4: breast carcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.