| Product Number |
OAAB17371 |
| Product Page |
www.avivasysbio.com/pi3kc2b-antibody-n-terminal-region-oaab17371.html |
| Name |
PI3KC2B Antibody - N-terminal region (OAAB17371) |
| Molecular Weight |
184768 Da |
| Isotype |
Ig |
| NCBI Gene Id |
5287 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
C2-PI3K |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17371 |
| Additional Information |
Precautions: PI3KC2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades |
| Application Info |
IHC-P: 1:10~50 |
| Immunogen |
This PI3KC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-150 amino acids from the N-terminal region of human PI3KC2B. |
| Additional Information |
Cellular Location: Microsome. Cell membrane. Cytoplasm, cytosol. Nucleus. Endoplasmic reticulum. Note=Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis
Tissue Location: Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level). Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney |
| Uniprot ID |
O00750 |
| Protein Name |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
| Protein Accession # |
NP_002637.3 |
| Gene Symbol |
PIK3C2B |
| Predicted Species Reactivity |
Human |
| Application |
IHC |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Human breast carcinoma
 | Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PI3KC2B antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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