| Product Number |
OAAB17365 |
| Product Page |
www.avivasysbio.com/mlk4-antibody-n-terminal-region-oaab17365.html |
| Name |
MLK4 Antibody - N-terminal region (OAAB17365) |
| Molecular Weight |
113957 Da |
| Isotype |
Ig |
| NCBI Gene Id |
84451 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
MLK4, dJ862P8.3 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17365 |
| Additional Information |
Precautions: MLK4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways |
| Application Info |
WB: 1:1000
IHC-P: 1:10~50 |
| Immunogen |
This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4. |
| Uniprot ID |
Q5TCX8 |
| Protein Name |
Mitogen-activated protein kinase kinase kinase MLK4 |
| Protein Accession # |
NP_115811.2 |
| Gene Symbol |
MLK4 |
| Predicted Species Reactivity |
Human |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Human colon carcinoma
 | Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MLK4 antibody (N-term) (Cat.# OAAB17365), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
| | Image 2 | 293
 | Western blot analysis of MLK4 (arrow) using rabbit polyclonal MLK4 Antibody (N-term) (Cat.# OAAB17365). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KIAA1804 gene (Lane 2) (Origene Technologies). |
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