| Product Number |
OAAB17353 |
| Product Page |
www.avivasysbio.com/nik-antibody-center-region-oaab17353.html |
| Name |
NIK Antibody - middle region (OAAB17353) |
| Molecular Weight |
104042 Da |
| Isotype |
Ig |
| NCBI Gene Id |
9020 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
HS, NIK, HSNIK, FTDCR1B |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17353 |
| Additional Information |
Precautions: NIK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non- canonical pathway. Could act in a receptor-selective manner |
| Application Info |
WB: 1:1000
IHC-P: 1:50~100 |
| Immunogen |
This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK. |
| Additional Information |
Cellular Location: Cytoplasm.
Tissue Location: Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon |
| Uniprot ID |
Q99558 |
| Protein Name |
Mitogen-activated protein kinase kinase kinase 14 |
| Protein Accession # |
NP_003945.2 |
| Gene Symbol |
MAP3K14 |
| Predicted Species Reactivity |
Human, Rat |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human; Rat |
| Image 1 | 293, Rat Testis
 | The anti-NIK Pab (Cat. # OAAB17353) is used in Western blot to detect NIK in 293 cell lysate (Lane 1) and rat testis tissue lysate (Lane 2). |
| | Image 2 | breast carcinoma
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
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