SGK2 Antibody - C-terminal region (OAAB17336)

• Product Number: OAAB17336
• Name: SGK2 Antibody - C-terminal region (OAAB17336)
• Molecular Weight: 47604 Da
• Isotype: Ig
• NCBI Gene Id: 10110
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: H-SGK2, dJ138B7.2
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: SGK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This SGK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-426 amino acids from the C-terminal region of human SGK2.
• Additional Information: Cellular Location: Cytoplasm. Nucleus.
  Tissue Location: Highly expressed in liver, kidney and pancreas, and at lower levels in brain
• Uniprot ID: Q9HBY8
• Protein Name: Serine/threonine-protein kinase Sgk2
• Protein Accession #: NP_001186193.1
• Gene Symbol: SGK2
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Placenta
  
  Western blot analysis of anti-SKG2 Pab (Cat. # OAAB17336) in placenta lysate. SKG2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
• Image 2: breast carcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.