| Product Number |
OAAB17229 |
| Product Page |
www.avivasysbio.com/matk-antibody-n-terminal-region-oaab17229.html |
| Name |
MATK Antibody - N-terminal region (OAAB17229) |
| Molecular Weight |
56469 Da |
| Isotype |
Ig |
| NCBI Gene Id |
4145 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
CHK, CTK, HYL, Lsk, HYLTK, HHYLTK |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17229 |
| Additional Information |
Precautions: MATK Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation |
| Application Info |
WB: 1:1000 |
| Immunogen |
This MATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MATK. |
| Additional Information |
Cellular Location: Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation
Tissue Location: Expressed in various myeloid cell lines, detected in brain and lung |
| Uniprot ID |
P42679 |
| Protein Name |
Megakaryocyte-associated tyrosine-protein kinase |
| Sample Type Confirmation |
MATK is strongly supported by BioGPS gene expression data to be expressed in HL60 |
| Protein Accession # |
NP_002369.2 |
| Gene Symbol |
MATK |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | HL-60
 | MATK Antibody (M1) (Cat. # OAAB17229) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MATK antibody detected the MATK protein (arrow). MATK is strongly supported by BioGPS gene expression data to be expressed in HL60 |
|
