STK33 Antibody - C-terminal region (OAAB17195)

• Product Number: OAAB17195
• Name: STK33 Antibody - C-terminal region (OAAB17195)
• Molecular Weight: 57831 Da
• Isotype: Ig
• NCBI Gene Id: 65975
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: STK33, Serine/threonine-protein kinase 33
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: STK33 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for the survival of KRAS-dependent AML cell lines
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This STK33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-506 amino acids from the C-terminal region of human STK33.
• Additional Information: Cellular Location: Cytoplasm, perinuclear region (By similarity)
  Tissue Location: Highly expressed in testis, fetal lung and heart, followed by pituitary gland, kidney, interventricular septum, pancreas, heart, trachea, thyroid gland and uterus. Weak hybridization signals were observed in the following tissues: amygdala, aorta, esophagus, colon ascending, colon transverse, skeletal muscle, spleen, peripheral blood leukocyte, lymph node, bone marrow, placenta, prostate, liver, s
• Uniprot ID: Q9BYT3
• Protein Name: Serine/threonine-protein kinase 33
• Protein Accession #: NP_112168.1
• Gene Symbol: STK33
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: NCI-H460
  
  STK33-T481 (Cat. # OAAB17195) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the STK33 antibody detected the STK33 protein (arrow).
• Image 2: hepatocarcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.