ROR2 Antibody - N-terminal region (OAAB17187)

• Product Number: OAAB17187
• Name: ROR2 Antibody - N-terminal region (OAAB17187)
• Molecular Weight: 104757 Da
• Isotype: Ig
• NCBI Gene Id: 4920
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: BDB, BDB1, NTRKR2
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Function: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation
• Additional Information: Cellular Location: Cell membrane; Single-pass type I membrane protein (By similarity)
• Application Info: WB: 1:1000
  IHC-P: 1:10~50
  FC: 1:10~50
• Immunogen: This ROR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-50 amino acids from the N-terminal region of human ROR2.
• Intended Use: ROR2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Uniprot ID: Q01974
• Protein Name: Tyrosine-protein kinase transmembrane receptor ROR2
• Sample Type Confirmation:

  ROR2 is strongly supported by BioGPS gene expression data to be expressed in HEK293

• Protein Accession #: NP_004551.2
• Gene Symbol: ROR2
• Predicted Species Reactivity: Human
• Application: WB, IHC, FC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Transfected 293 cell
  
  Western blot analysis of ROR2 (arrow) using rabbit polyclonal ROR2 Antibody (N-term) (Cat.#OAAB17187). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ROR2 gene (Lane 2) (Origene Technologies).
• Image 2: human kidney carcinoma
  
  Formalin-fixed and paraffin-embedded human kidney carcionma reacted with ROR2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
• Image 3: NCI-H292 cell
  
  Flow cytometric analysis of NCI-H292 cells using ROR2 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.