Insulin Receptor R Antibody - N-terminal region (OAAB17170)

Data Sheet
 
Product Number OAAB17170
Product Page www.avivasysbio.com/insulin-receptor-r-antibody-n-terminal-region-oaab17170.html
Name Insulin Receptor R Antibody - N-terminal region (OAAB17170)
Molecular Weight 143720 Da
Isotype Ig
NCBI Gene Id 3645
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols IRR
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Description of Target Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB17170
Additional Information Precautions: Insulin Receptor R Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB
Application Info WB: 1:2000
WB: 1:1000
IHC-P: 1:10~50
Immunogen This Insulin Receptor R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-57 amino acids from the N-terminal region of human Insulin Receptor R.
Additional Information Cellular Location: Membrane; Single-pass type I membrane protein
Uniprot ID P14616
Protein Name Insulin receptor-related protein
Protein Accession # NP_055030.1
Gene Symbol INSRR
Predicted Species Reactivity Human, Mouse
Application IHC-P, WB
Predicted Homology Based on Immunogen Sequence Human; Mouse
Image 1
Mouse Brain
Western blot analysis of anti-INSRR Pab (Cat. # OAAB17170) in mouse brain lysate. INSRR (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Image 2
Human Testis
Formalin-fixed and paraffin-embedded human testis tissue reacted with INSRR antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
 

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