| Product Number |
OAAB17170 |
| Product Page |
www.avivasysbio.com/insulin-receptor-r-antibody-n-terminal-region-oaab17170.html |
| Name |
Insulin Receptor R Antibody - N-terminal region (OAAB17170) |
| Molecular Weight |
143720 Da |
| Isotype |
Ig |
| NCBI Gene Id |
3645 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
IRR |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17170 |
| Additional Information |
Precautions: Insulin Receptor R Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB |
| Application Info |
WB: 1:2000
WB: 1:1000
IHC-P: 1:10~50 |
| Immunogen |
This Insulin Receptor R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-57 amino acids from the N-terminal region of human Insulin Receptor R. |
| Additional Information |
Cellular Location: Membrane; Single-pass type I membrane protein |
| Uniprot ID |
P14616 |
| Protein Name |
Insulin receptor-related protein |
| Protein Accession # |
NP_055030.1 |
| Gene Symbol |
INSRR |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
| Image 1 | Mouse Brain
 | Western blot analysis of anti-INSRR Pab (Cat. # OAAB17170) in mouse brain lysate. INSRR (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
| | Image 2 | Human Testis
 | Formalin-fixed and paraffin-embedded human testis tissue reacted with INSRR antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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