PSKH1 Antibody - N-terminal region (Phospho-H70) (OAAB16950)

• Product Number: OAAB16950
• Name: PSKH1 Antibody - N-terminal region (Phospho-H70) (OAAB16950)
• Molecular Weight: 48035 Da
• Isotype: Ig
• NCBI Gene Id: 5681
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: PSKH1, Serine/threonine-protein kinase H1, Protein serine kinase H1
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: PSKH1 Antibody (N-term H70) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This PSKH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-91 amino acids from the N-terminal region of human PSKH1.
• Additional Information: Cellular Location: Golgi apparatus. Cytoplasm, cytoskeleton, centrosome. Nucleus speckle. Endoplasmic reticulum membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Cytoplasm Note=Localized in the brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the c
  Tissue Location: Expressed in all tissues and cell lines tested with the highest level of abundance in testis
• Uniprot ID: P11801
• Protein Name: Serine/threonine-protein kinase H1
• Protein Accession #: NP_006733.1
• Gene Symbol: PSKH1
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Human cancer, breast carcinoma, hepatocarcinoma
  
  Western blot analysis of anti-PSKH1 Antibody (N-term H70) (Cat.# OAAB16950) in Hela cell line lysate and mouse kidney tissue lysate (35ug/lane). PSKH1 (arrow) was detected using the purified Pab.
• Image 2: human cancer
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.