NME3 Antibody - middle region (OAAB16923)

Data Sheet
 
Product Number OAAB16923
Product Page www.avivasysbio.com/nme3-antibody-center-region-oaab16923.html
Name NME3 Antibody - middle region (OAAB16923)
Molecular Weight 19015 Da
Isotype Ig
NCBI Gene Id 4832
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols NDPKC, NDPK-C, NM23H3, DR-nm23, NM23-H3, c371H6.2
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Description of Target Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16923
Additional Information Precautions: NME3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis
Application Info WB: 1:1000
IHC-P: 1:50~100
Immunogen This NME3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the Central region of human NME3.
Uniprot ID Q13232
Protein Name Nucleoside diphosphate kinase 3
Protein Accession # NP_002504.2
Gene Symbol NME3
Predicted Species Reactivity Human
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Human
Image 1
CEM
Western blot analysis of anti-NME3 Pab (Cat. # OAAB16923) in CEM cell line tissue lysate (35ug/lane).NME3(arrow) was detected using the purified Pab (1:40 dilution).
Image 2
breast carcinoma
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
 

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