ERN2 Antibody - N-terminal region (OAAB16894)

• Product Number: OAAB16894
• Name: ERN2 Antibody - N-terminal region (OAAB16894)
• Molecular Weight: 102480 Da
• Isotype: Ig
• NCBI Gene Id: 10595
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: IRE1b, IRE2p, hIRE2p, IRE1-BETA
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: ERN2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins
• Application Info: WB: 1:1000
• Immunogen: This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2.
• Additional Information: Cellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein
• Uniprot ID: Q76MJ5
• Protein Name: Serine/threonine-protein kinase/endoribonuclease IRE2
• Protein Accession #: NP_150296.3
• Gene Symbol: ERN2
• Predicted Species Reactivity: Human
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Mouse Stomach
  
  Western blot analysis of ERN2 N-term (Cat. # OAAB16894) in mouse stomach tissue lysates (35ug/lane). ERN2 (arrow) was detected using the purified Pab.