PICK1 Antibody - C-terminal region (OAAB16831)

Data Sheet
 
Product Number OAAB16831
Product Page www.avivasysbio.com/pick1-prkcabp-antibody-c-terminal-region-oaab16831.html
Name PICK1 Antibody - C-terminal region (OAAB16831)
Molecular Weight 46600 Da
Isotype Ig
NCBI Gene Id 9463
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols PICK, PRKCABP
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Description of Target Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16831
Additional Information Precautions: PICK1 (PRKCABP) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ASIC1/ASIC3 channel
Application Info WB: 1:1000
Immunogen This PICK1 (PRKCABP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-316 amino acids from the C-terminal region of human PICK1 (PRKCABP).
Additional Information Cellular Location: Cytoplasm, perinuclear region. Cell junction, synapse. Note=Also present at excitatory synapses
Tissue Location: Ubiquitous.
Uniprot ID Q9NRD5
Protein Name PRKCA-binding protein
Protein Accession # NP_001034672.1
Gene Symbol PICK1
Predicted Species Reactivity Human, Mouse
Application WB
Predicted Homology Based on Immunogen Sequence Human; Mouse
Image 1
HL-60, Jurkat, K562
Western blot analysis of hPRKCABP-C300 (Cat.# OAAB16831) in HL-60, Jurkat, K562 cell line lysates (35ug/lane). PRKCABP (arrow) was detected using the purified Pab.
 

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