Product Number |
OAAB16786 |
Product Page |
www.avivasysbio.com/ampk-beta2-prkab2-antibody-n-terminal-region-oaab16786.html |
Name |
PRKAB2 Antibody - N-terminal region (OAAB16786) |
Molecular Weight |
30302 Da |
Isotype |
Ig |
NCBI Gene Id |
5565 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
PRKAB2, 5'-AMP-activated protein kinase subunit beta-2 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16786 |
Additional Information |
Precautions: AMPK beta2 (PRKAB2) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) |
Application Info |
WB: 1:1000 |
Immunogen |
This AMPK beta2 (PRKAB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human AMPK beta2 (PRKAB2). |
Uniprot ID |
O43741 |
Protein Name |
5'-AMP-activated protein kinase subunit beta-2 |
Protein Accession # |
NP_005390.1 |
Gene Symbol |
PRKAB2 |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | Mouse Kidney
| PRKAB2 Antibody (A18) (Cat. # OAAB16786) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PRKAB2 antibody detected the PRKAB2 protein (arrow). |
| Image 2 | A375
| PRKAB2 Antibody (A18) (Cat. # OAAB16786) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the PRKAB2 antibody detected the PRKAB2 protein (arrow). |
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