Product Number |
OAAB16705 |
Product Page |
www.avivasysbio.com/synphilin-1-sncaip-antibody-c-terminal-region-oaab16705.html |
Name |
SNCAIP Antibody - C-terminal region (OAAB16705) |
Molecular Weight |
100409 Da |
Isotype |
Ig |
NCBI Gene Id |
9627 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
Sph1, SYPH1 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16705 |
Additional Information |
Precautions: Synphilin-1 (SNCAIP) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1 |
Application Info |
WB: 1:1000 |
Immunogen |
This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP). |
Additional Information |
Cellular Location: Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA Tissue Location: Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta |
Uniprot ID |
Q9Y6H5 |
Protein Name |
Synphilin-1 |
Protein Accession # |
NP_001229864.1 |
Gene Symbol |
SNCAIP |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | Mouse Brain
| The anti-Synphilin-1 C-term Pab (Cat. # OAAB16705) is used in Western blot to detect Synphilin-1 in mouse brain lysate. |
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