Product Number |
OAAB16689 |
Product Page |
www.avivasysbio.com/zbtb7b-antibody-center-region-oaab16689.html |
Name |
ZBTB7B Antibody - middle region (OAAB16689) |
Molecular Weight |
58027 Da |
Isotype |
Ig |
NCBI Gene Id |
51043 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
CKROX, THPOK, ZFP67, ZBTB15, ZFP-67, c-KROX, hcKROX, ZNF857B |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16689 |
Additional Information |
Precautions: ZBTB7B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity) |
Application Info |
WB: 1:1000 IHC-P: 1:50 |
Immunogen |
This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the Central region of human ZBTB7B. |
Additional Information |
Cellular Location: Nucleus. |
Uniprot ID |
O15156 |
Protein Name |
Zinc finger and BTB domain-containing protein 7B |
Protein Accession # |
NP_001239335.1 |
Gene Symbol |
ZBTB7B |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | Mouse Brain
| Western blot analysis of ZBTB7B Antibody (Center) Pab (Cat.# OAAB16689) in mouse brain tissue lysates (35ug/lane). ZBTB7B (arrow) was detected using the purified Pab (1:60 dilution). |
| Image 2 | Human hepatocarcinoma
| Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center) (Cat.# OAAB16689), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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