ZBTB7B Antibody - middle region (OAAB16689)

Data Sheet
 
Product Number OAAB16689
Product Page www.avivasysbio.com/zbtb7b-antibody-center-region-oaab16689.html
Name ZBTB7B Antibody - middle region (OAAB16689)
Molecular Weight 58027 Da
Isotype Ig
NCBI Gene Id 51043
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols CKROX, THPOK, ZFP67, ZBTB15, ZFP-67, c-KROX, hcKROX, ZNF857B
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Description of Target Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16689
Additional Information Precautions: ZBTB7B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity)
Application Info WB: 1:1000
IHC-P: 1:50
Immunogen This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the Central region of human ZBTB7B.
Additional Information Cellular Location: Nucleus.
Uniprot ID O15156
Protein Name Zinc finger and BTB domain-containing protein 7B
Protein Accession # NP_001239335.1
Gene Symbol ZBTB7B
Predicted Species Reactivity Human, Mouse
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Human; Mouse
Image 1
Mouse Brain
Western blot analysis of ZBTB7B Antibody (Center) Pab (Cat.# OAAB16689) in mouse brain tissue lysates (35ug/lane). ZBTB7B (arrow) was detected using the purified Pab (1:60 dilution).
Image 2
Human hepatocarcinoma
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody (Center) (Cat.# OAAB16689), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
 

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