| Product Number |
OAAB16560 |
| Product Page |
www.avivasysbio.com/nrg2-antibody-c-terminal-region-oaab16560.html |
| Name |
NRG2 Antibody - C-terminal region (OAAB16560) |
| Molecular Weight |
91679 Da |
| Isotype |
Ig |
| NCBI Gene Id |
9542 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
DON1, HRG2, NTAK |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16560 |
| Additional Information |
Precautions: NRG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor |
| Application Info |
WB: 1:1000
IHC-P: 1:50~100 |
| Immunogen |
This NRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2. |
| Additional Information |
Cellular Location: Pro-neuregulin-2, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein (By similarity). Note=Does not seem to be active (By similarity)
Tissue Location: Restricted to the cerebellum in the adult. |
| Uniprot ID |
O14511 |
| Protein Name |
Pro-neuregulin-2, membrane-bound isoform |
| Protein Accession # |
NP_001171864.1 |
| Gene Symbol |
NRG2 |
| Predicted Species Reactivity |
Human, Rat |
| Application |
IHC |
| Predicted Homology Based on Immunogen Sequence |
Human; Rat |
| Image 1 | hepatocarcinoma
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
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