Product Number |
OAAB16538 |
Product Page |
www.avivasysbio.com/mmp11-antibody-c-terminal-region-oaab16538.html |
Name |
MMP11 Antibody - C-terminal region (OAAB16538) |
Molecular Weight |
54590 Da |
Isotype |
Ig |
NCBI Gene Id |
4320 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
ST3, SL-3, STMY3 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Description of Target |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP11 may play an important role in the progression of epithelial malignancies. It is specifically expressed in stromal cells of breast carcinomas. |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16538 |
Additional Information |
Function: May play an important role in the progression of epithelial malignancies Cellular Location: Secreted, extracellular space, extracellular matrix Tissue Location: Specifically expressed in stromal cells of breast carcinomas |
Application Info |
WB: 1:1000 |
Immunogen |
This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-426 amino acids from the C-terminal region of human MMP11. |
Intended Use |
MMP11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Uniprot ID |
P24347 |
Protein Name |
Stromelysin-3 |
Sample Type Confirmation |
There is BioGPS gene expression data showing that MMP11 is expressed in HEK293 |
Protein Accession # |
NP_005931.2 |
Purification |
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Gene Symbol |
MMP11 |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | 293
| Western blot analysis of anti-MMP11 Antibody (C-term) (Cat.# OAAB16538) in 293 cell line lysates (35ug/lane). MMP11(arrow) was detected using the purified Pab. There is BioGPS gene expression data showing that MMP11 is expressed in HEK293 |
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