| Product Number |
OAAB16501 |
| Product Page |
www.avivasysbio.com/leptin-lep-antibody-c-terminal-region-oaab16501.html |
| Name |
LEP Antibody - C-terminal region (OAAB16501) |
| Molecular Weight |
18641 Da |
| Isotype |
Ig |
| NCBI Gene Id |
3952 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
OB, OBS, LEPD |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16501 |
| Additional Information |
Precautions: Leptin (LEP) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass |
| Application Info |
WB: 1:1000
IF: 1:10~50 |
| Immunogen |
This Leptin (LEP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the C-terminal region of human Leptin (LEP). |
| Additional Information |
Cellular Location: Secreted. |
| Uniprot ID |
P41159 |
| Protein Name |
Leptin |
| Sample Type Confirmation |
LEP is strongly supported by BioGPS gene expression data to be expressed in MDA-MB231 |
| Protein Accession # |
NP_000221.1 |
| Gene Symbol |
LEP |
| Predicted Species Reactivity |
Human |
| Application |
WB, IF |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | MDA-MB231
 | Western blot analysis of hLep-R149 (Cat. # OAAB16501) in MDA-MB231 cell line lysates (35ug/lane). LEP (arrow) was detected using the purified Pab. LEP is strongly supported by BioGPS gene expression data to be expressed in MDA-MB231 |
| | Image 2 | HepG2, Nuclear
 | HepG2, Nuclear |
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