| Product Number |
OAAB16494 |
| Product Page |
www.avivasysbio.com/edg2-antibody-n-terminal-region-oaab16494.html |
| Name |
EDG2 Antibody - N-terminal region (OAAB16494) |
| Molecular Weight |
41109 Da |
| Isotype |
Ig |
| NCBI Gene Id |
1902 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
EDG2, LPA1, VZG1, edg-2, vzg-1, Gpcr26, Mrec1.3, rec.1.3 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16494 |
| Additional Information |
Precautions: EDG2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation |
| Application Info |
WB: 1:1000 |
| Immunogen |
This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2. |
| Additional Information |
Cellular Location: Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles
Tissue Location: Expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes |
| Uniprot ID |
Q92633 |
| Protein Name |
Lysophosphatidic acid receptor 1 |
| Protein Accession # |
NP_001392.2 |
| Gene Symbol |
LPAR1 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | A375
 | The anti-EDG2 N-term Antibody (Cat.# OAAB16494) is used in Western blot to detect EDG2 in A375 lysate. |
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