HNRPDL Antibody - middle region (OAAB16453)

Data Sheet
 
Product Number OAAB16453
Product Page www.avivasysbio.com/hnrpdl-antibody-center-region-oaab16453.html
Name HNRPDL Antibody - middle region (OAAB16453)
Molecular Weight 46438 Da
Isotype Ig
NCBI Gene Id 9987
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols HNRNP, JKTBP, HNRPDL, JKTBP2, LGMD1G, LGMDD3, laAUF1
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16453
Additional Information Precautions: HNRPDL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity) Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence
Application Info WB: 1:1000
Immunogen This HNRPDL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human HNRPDL.
Additional Information Cellular Location: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner
Tissue Location: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes Expressed in myeloid leukemia, gastric adenocarcinoma, cervical carcinoma, hepatoma, fibrosarcoma, colon adenocarcinoma, epidermoid carcinoma, osteosarcoma and urinary bladder carcinoma cells
Uniprot ID O14979
Protein Name Heterogeneous nuclear ribonucleoprotein D-like
Sample Type Confirmation

HNRPDL is strongly supported by BioGPS gene expression data to be expressed in HepG2, Jurkat, K562

Protein Accession # NP_001193929.1
Gene Symbol HNRPDL
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Human
Image 1
HepG2, Jurkat, K562
HNRPDL Antibody (Center) (Cat. # OAAB16453) western blot analysis in K562,HepG2,Jurkat cell line lysates (35ug/lane).This demonstrates the HNRPDL antibody detected the HNRPDL protein (arrow).

HNRPDL is strongly supported by BioGPS gene expression data to be expressed in HepG2, Jurkat, K562

 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
10211 Pacific Mesa Blvd, Ste 401, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com