Product Number |
OAAB16453 |
Product Page |
www.avivasysbio.com/hnrpdl-antibody-center-region-oaab16453.html |
Name |
HNRPDL Antibody - middle region (OAAB16453) |
Molecular Weight |
46438 Da |
Isotype |
Ig |
NCBI Gene Id |
9987 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
HNRNP, JKTBP, HNRPDL, JKTBP2, LGMD1G, LGMDD3, laAUF1 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16453 |
Additional Information |
Precautions: HNRPDL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity) Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence |
Application Info |
WB: 1:1000 |
Immunogen |
This HNRPDL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human HNRPDL. |
Additional Information |
Cellular Location: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner Tissue Location: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes Expressed in myeloid leukemia, gastric adenocarcinoma, cervical carcinoma, hepatoma, fibrosarcoma, colon adenocarcinoma, epidermoid carcinoma, osteosarcoma and urinary bladder carcinoma cells |
Uniprot ID |
O14979 |
Protein Name |
Heterogeneous nuclear ribonucleoprotein D-like |
Sample Type Confirmation |
HNRPDL is strongly supported by BioGPS gene expression data to be expressed in HepG2, Jurkat, K562 |
Protein Accession # |
NP_001193929.1 |
Gene Symbol |
HNRPDL |
Predicted Species Reactivity |
Human |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human |
Image 1 | HepG2, Jurkat, K562
| HNRPDL Antibody (Center) (Cat. # OAAB16453) western blot analysis in K562,HepG2,Jurkat cell line lysates (35ug/lane).This demonstrates the HNRPDL antibody detected the HNRPDL protein (arrow). HNRPDL is strongly supported by BioGPS gene expression data to be expressed in HepG2, Jurkat, K562 |
|