beclin 1 Antibody (Phospho-Ser64) (OAAB16385)

Data Sheet
 
Product Number OAAB16385
Product Page www.avivasysbio.com/beclin-1-antibody-phospho-s64-oaab16385.html
Name beclin 1 Antibody (Phospho-Ser64) (OAAB16385)
Molecular Weight 51896 Da
Isotype Ig
NCBI Gene Id 8678
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols ATG6, VPS30, beclin1
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16385
Additional Information Precautions: beclin 1 Antibody (Phospho S64) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus
Application Info DB: 1:500
Immunogen This beclin 1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S64 of human beclin 1.
Additional Information Cellular Location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity)
Tissue Location: Ubiquitous.
Uniprot ID Q14457
Protein Name Beclin-1
Protein Accession # NP_003757.1
Gene Symbol BECN1
Predicted Species Reactivity Human
Application DB
Predicted Homology Based on Immunogen Sequence Human
Image 1
Phospho-peptide, non-phospho-peptide
Dot blot analysis of beclin 1 Antibody (Phospho S64) Phospho-specific Pab (Cat. # OAAB16385) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
 

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