TSC1 Antibody (Phospho-Tyr304) (OAAB16369)

Data Sheet
 
Product Number OAAB16369
Product Page www.avivasysbio.com/mouse-tsc1-phospho-y304-antibody-oaab16369.html
Name TSC1 Antibody (Phospho-Tyr304) (OAAB16369)
Molecular Weight 128746 Da
Isotype Ig
NCBI Gene Id 64930
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols ham
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16369
Additional Information Precautions: mouse TSC1 (Phospho Y304) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity)
Application Info DB: 1:500
Immunogen This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y304 of mouse TSC1.
Additional Information Cellular Location: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). Note=At steady state found in association with membranes (By similarity)
Uniprot ID Q9EP53
Protein Name Hamartin
Protein Accession # NP_075025.2
Gene Symbol Tsc1
Predicted Species Reactivity Mouse
Application DB
Predicted Homology Based on Immunogen Sequence Mouse
Image 1
Phospho-peptide, non-phospho-peptide
Dot blot analysis of mouse TSC1 Antibody (Phospho Y304) Phospho-specific Pab (Cat. # OAAB16369) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
 

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