BAD Antibody (Phospho-Ser34) (OAAB16252)

Data Sheet
 
Product Number OAAB16252
Product Page www.avivasysbio.com/bad-antibody-phospho-s34-oaab16252.html
Name BAD Antibody (Phospho-Ser34) (OAAB16252)
Molecular Weight 18392 Da
Isotype Ig
NCBI Gene Id 572
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols BBC2, BCL2L8
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16252
Additional Information Precautions: Phospho-BAD-S34 is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways
Application Info DB: 1:500
Immunogen This BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S34 of human BAD.
Additional Information Cellular Location: Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
Tissue Location: Expressed in a wide variety of tissues.
Uniprot ID Q92934
Protein Name Bcl2 antagonist of cell death
Protein Accession # NP_004313.1
Gene Symbol BAD
Predicted Species Reactivity Human
Application DB
Predicted Homology Based on Immunogen Sequence Human
Image 1
Phospho-peptide, non-phospho-peptide
Dot blot analysis of Phospho-BAD-S34 Antibody Phospho-specific Pab (Cat. # OAAB16252) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
 

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