| Product Number |
OAAB16239 |
| Product Page |
www.avivasysbio.com/amot-antibody-phospho-s1041-oaab16239.html |
| Name |
AMOT Antibody (Phospho-Ser1041) (OAAB16239) |
| Molecular Weight |
118085 Da |
| Isotype |
Ig |
| NCBI Gene Id |
154796 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
AMOT, KIAA1071, Angiomotin |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16239 |
| Additional Information |
Precautions: Phospho-AMOT-S1041 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions |
| Application Info |
DB: 1:500 |
| Immunogen |
This AMOT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1041 of human AMOT. |
| Additional Information |
Cellular Location: Cell junction, tight junction. Note=Localized on the cell surface. May act as a transmembrane protein
Tissue Location: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta |
| Uniprot ID |
Q4VCS5 |
| Protein Name |
Angiomotin |
| Protein Accession # |
NP_001106962.1 |
| Gene Symbol |
AMOT |
| Predicted Species Reactivity |
Human |
| Application |
DB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Phospho-peptide, non-phospho-peptide
 | Dot blot analysis of Phospho-AMOT-S1041 Antibody Phospho-specific Pab (Cat. # OAAB16239) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
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