| Product Number |
OAAB16222 |
| Product Page |
www.avivasysbio.com/jmjd2b-antibody-phospho-s566-oaab16222.html |
| Name |
JMJD2B Antibody (Phospho-Ser566) (OAAB16222) |
| Molecular Weight |
121897 Da |
| Isotype |
Ig |
| NCBI Gene Id |
23030 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
JMJD2B, TDRD14B |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16222 |
| Additional Information |
Precautions: Phospho-JMJD2B-S566 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate |
| Application Info |
DB: 1:500 |
| Immunogen |
This JMJD2B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S566 of human JMJD2B. |
| Additional Information |
Cellular Location: Nucleus. |
| Uniprot ID |
O94953 |
| Protein Name |
Lysine-specific demethylase 4B |
| Protein Accession # |
NP_055830.1 |
| Gene Symbol |
KDM4B |
| Predicted Species Reactivity |
Human |
| Application |
DB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Phospho-peptide, non-phospho-peptide
 | Dot blot analysis of anti-Phospho-JMJD2B-S566 Phospho-specific Pab (Cat. # OAAB16222) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
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