| Product Number |
OAAB16198 |
| Product Page |
www.avivasysbio.com/atf2-antibody-phospho-s322-oaab16198.html |
| Name |
ATF2 Antibody (Phospho-Ser322) (OAAB16198) |
| Molecular Weight |
54537 Da |
| Isotype |
Ig |
| NCBI Gene Id |
1386 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
HB16, CREB2, TREB7, CREB-2, CRE-BP1 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16198 |
| Additional Information |
Precautions: Phospho-ATF2-S322 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'- GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex |
| Application Info |
DB: 1:500 |
| Immunogen |
This ATF2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S322 of human ATF2. |
| Additional Information |
Cellular Location: Nucleus.
Tissue Location: Abundant expression seen in the brain. |
| Uniprot ID |
P15336 |
| Protein Name |
Cyclic AMP-dependent transcription factor ATF-2 |
| Protein Accession # |
NP_001243019.1 |
| Gene Symbol |
ATF2 |
| Predicted Species Reactivity |
Human |
| Application |
DB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Phospho-peptide, non-phospho-peptide
 | Dot blot analysis of Phospho-ATF2-S322 Antibody (Cat. # OAAB16198) and ATF2 Non Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
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