FOS Antibody (Phospho-Thr232) (OAAB16155)

Data Sheet
 
Product Number OAAB16155
Product Page www.avivasysbio.com/fos-antibody-phospho-t232-oaab16155.html
Name FOS Antibody (Phospho-Thr232) (OAAB16155)
Molecular Weight 40695 Da
Isotype Ig
NCBI Gene Id 2353
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols p55, AP-1, C-FOS
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16155
Additional Information Precautions: Phospho-FOS-T232 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD- binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation
Application Info DB: 1:500
Immunogen This FOS Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T232 of human FOS.
Additional Information Cellular Location: Nucleus.
Uniprot ID P01100
Protein Name Proto-oncogene c-Fos
Protein Accession # NP_005243.1
Gene Symbol FOS
Predicted Species Reactivity Human
Application DB
Predicted Homology Based on Immunogen Sequence Human
Image 1
Phospho-peptide, non-phospho-peptide
Dot blot analysis of Phospho-FOS-T232 polyclonal antibody (Cat# OAAB16155) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5ug per ml. P-Pab: phospho-antibody; P-Peptide: phospho-peptide; NP-Peptide: non-phospho-peptide.
 

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