Product Number |
OAAB16155 |
Product Page |
www.avivasysbio.com/fos-antibody-phospho-t232-oaab16155.html |
Name |
FOS Antibody (Phospho-Thr232) (OAAB16155) |
Molecular Weight |
40695 Da |
Isotype |
Ig |
NCBI Gene Id |
2353 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
p55, AP-1, C-FOS |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16155 |
Additional Information |
Precautions: Phospho-FOS-T232 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD- binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation |
Application Info |
DB: 1:500 |
Immunogen |
This FOS Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T232 of human FOS. |
Additional Information |
Cellular Location: Nucleus. |
Uniprot ID |
P01100 |
Protein Name |
Proto-oncogene c-Fos |
Protein Accession # |
NP_005243.1 |
Gene Symbol |
FOS |
Predicted Species Reactivity |
Human |
Application |
DB |
Predicted Homology Based on Immunogen Sequence |
Human |
Image 1 | Phospho-peptide, non-phospho-peptide
| Dot blot analysis of Phospho-FOS-T232 polyclonal antibody (Cat# OAAB16155) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5ug per ml. P-Pab: phospho-antibody; P-Peptide: phospho-peptide; NP-Peptide: non-phospho-peptide. |
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