| Product Number |
OAAB16145 |
| Product Page |
www.avivasysbio.com/crk-antibody-phospho-s41-oaab16145.html |
| Name |
CRK Antibody (Phospho-Ser41) (OAAB16145) |
| Molecular Weight |
33831 Da |
| Isotype |
Ig |
| NCBI Gene Id |
1398 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
p38, CRKII |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16145 |
| Additional Information |
Precautions: Phospho-CRK-S41 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling |
| Application Info |
DB: 1:500 |
| Immunogen |
This CRK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S41 of human CRK. |
| Additional Information |
Cellular Location: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Translocated to the plasma membrane upon cell adhesion (By similarity) |
| Uniprot ID |
P46108 |
| Protein Name |
Adapter molecule crk |
| Protein Accession # |
NP_005197.3 |
| Gene Symbol |
CRK |
| Predicted Species Reactivity |
Human |
| Application |
DB |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Phospho-peptide, non-phospho-peptide
 | Dot blot analysis of Phospho-CRK-S41 polyclonal antibody (Cat# OAAB16145) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5ug per ml. P-Pab: phospho-antibody; P-Peptide: phospho-peptide; NP-Peptide: non-phospho-peptide. |
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